We went out to Tlaquepaque yesterday. I'd been there once before, but it was mostly for shopping and we didn't look around that much. There isn't much to see since it's a shopping and restaurant destination, but we still had fun poking around the parts that weren't for shopping and eating.
There are also some interesting art galleries and a few stores I like there, but mostly it's not really my thing. Tonala is better. The stores in Tlaquepaque that I do like are around Juarez by Francisco de Miranda and Alfareros. There's a tile store (one of the few we've found so far in Mexico), textiles, one with indigenous designs (including a unique but large and fairly expensive nativity that we'll keep in mind), and an art gallary my husband loved.
I like it when churches are decorated with things that are made locally, so the glass inside the churches was nice.